Microcirculatory perfusion and vascular reactivity are altered in post cardiac arrest patients, irrespective of target temperature management to 33°C vs 36°C

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0020. Microcirculatory perfusion and vascular reactivity are altered in post cardiac arrest patients, irrespective of target temperature management to 33° vs 36° (substudy TTM)

Introduction After cardiopulmonary resuscitation (CPR), following an out of hospital cardiac arrest (OHCA) hemodynamic failure is common, due to a combination of heart failure and ischemia reperfusion injury. Comatose post-cardiac arrest patients are treated on the intensive care unit (ICU) with mild therapeutic hypothermia (33°), nowadays referred to as target temperature management (TTM) for ...

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Post-cooling fever in post-cardiac arrest patients: post-cooling normothermia as part of target temperature management?

Experimental studies support that fever after ischaemic brain injury may not only be a surrogate marker for severe cerebral ischaemia but may also deteriorate pre-existent cerebral ischaemic damage and should therefore be treated [1,2]. Neurological damage after cardiac arrest (CA) still determines the final outcome and post-CA critical care focuses on maximal neuroprotection, the application o...

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Temperature management and modern post-cardiac arrest care.

Modern cardiopulmonary resuscitation (CPR) began in 1960, when clinicians translated observations about external chest compressions from the laboratory to patients.1 CPR increased survival for patients who had cardiopulmonary collapse outside of the operating room from none to a few. Incremental improvements in the survivorship from CPR occurred as more persons were trained in CPR and as defibr...

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The Aassociation between Pre-Cardiac Arrest Comorbidity and Unsuccessful Cardiopulmonary Resuscitation in Patients with Cardiac Arrest

Background and Objective: Patients suffering from cardiac arrest (CA) have poor prognosis and survival. The association of pre-arrest comorbidity with unsuccessful resuscitation in patients with CA is far from clear. The aim of the present study was to investigate the association between pre-existing comorbidity and unsuccessful resuscitation following CA in Iranian patients. Materials and Met...

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Cooling techniques for targeted temperature management post-cardiac arrest

This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2015 and co-published as a series in Critical Care. Other articles in the series can be found online at http://ccforum.com/series/annualupdate2015. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901.

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ژورنال

عنوان ژورنال: Resuscitation

سال: 2015

ISSN: 0300-9572

DOI: 10.1016/j.resuscitation.2014.09.025